Very similar values for pharmacokinetic parameters were witnessed in normal volunteers and in the affected individual inhabitants, employing a population pharmacokinetic method.
[seventy two][73] The Viagra identify is now so famous that lots of fake aphrodisiacs now get in touch with them selves "herbal viagra" or are offered as blue tablets imitating the shape and colour of copyright's merchandise. Viagra is additionally informally known as "vitamin V", "the blue tablet", or "blue diamond", along with different other nicknames.
This metabolite provides a PDE selectivity profile comparable to sildenafil and an in vitro potency for PDE5 approximately 50% of the guardian drug. Plasma concentrations of the metabolite are somewhere around 40% of All those seen for sildenafil, so the metabolite accounts for approximately twenty% of sildenafil's pharmacologic results.
When there were no significant adverse occasions possibly connected to blood pressure documented During this research, just one issue reported reasonable vasodilatation soon after both of those VIAGRA fifty mg and one hundred mg. There were no episodes of syncope described During this analyze.
Breastfeeding. Sildenafil passes into breast milk. Convey to your Health care provider if you are breastfeeding or decide to breastfeed. Your Health care provider will suggest you if you need to acquire sildenafil while breastfeeding.
Seksuell aktivitet kan være ekstra belastende for hjertet. Dersom du har hjerteproblemer eller tror du kan ha et hjerteproblem er det viktig at du opplyser om dette i samtalen med farmasøyten i apotek. Du bør ta en helsesjekk hos din fastlege så snart som mulig i løpet av de fileørste 6 månedene etter du har begynt å bruke Viagra Reseptfri.
The most common Uncomfortable side effects of sildenafil are stated beneath. These Unwanted side effects may perhaps fluctuate according to the ailment that is definitely getting dealt with. Convey to your healthcare provider In case you have any of such side effects that trouble you.
an erection that will not go away (priapism). When you've got an erection that lasts much more than 4 several hours, get health care help immediately. If It's not at all handled straight away, priapism can permanently damage your penis.
Sildenafil can be a strong and selective inhibitor of cGMP-specific phosphodiesterase type 5 (PDE5), which happens to be answerable for degradation of cGMP during the corpus cavernosum. The molecular structure of sildenafil is analogous to that of cGMP and functions being a competitive binding agent of PDE5 within the corpus cavernosum, resulting in more cGMP and increased penile reaction to sexual stimulation.
More powerful CYP3A4 inhibitors for instance ketoconazole or itraconazole might be anticipated to own larger consequences than seen with saquinavir. A commencing dose of 25 mg of VIAGRA must be viewed as in more info people getting erythromycin or solid CYP3A4 inhibitors (for example saquinavir, ketoconazole, itraconazole) [see DOSAGE AND ADMINISTRATION, Medical PHARMACOLOGY].
Bruk ikke Viagra Reseptfri dersom du er allergisk mot sildenafil eller noen av de andre innholdsstoffene.
Sildenafil really should not be employed if sexual action is inadvisable as a consequence of underlying cardiovascular chance components.[31]
Viagra is meant for use in Adult men, and is particularly unlikely to be used in Women of all ages who are Expecting or breastfeeding. However, Viagra is not really predicted for being dangerous to the fetus.
nett (99+) apotek Dette produktet hentes i apotek ved bestilling på nett Legg til som favoritt